Bone Marrow Aspiration Device
Aspirate from multiple sites through a single access point, without a centrifuge — while limiting peripheral blood dilution.
Aspirates freely from the open end — drawing peripheral blood alongside marrow at a single anatomical site and diluting the cellular yield.
Forces 100% of aspiration through precision side ports — preventing peripheral blood dilution and obtaining higher cell counts from intact cancellous bone.
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CFU-f counts and Total Nucleated Cell density track side by side with autograft across four independent studies (n = 37 pooled).
Mesenchymal Stem and Progenitor Cell Density
Total Nucleated Cells
Individual sample results from each study making up the pooled Cervos BMA n=37 cohort.
| Study | Device / System | Sample Size n |
CFU-f per mL |
TNC ×106 per mL |
|---|---|---|---|---|
| Muschler1 | Cancellous Bone Autograft (gold standard) | 10 | 4,564 | 55.7 |
| Lutz5 | Cervos BMA — Marrow Cellution | 22 | 4,838 | 47.0 |
| Scarpone4 | Cervos BMA — Marrow Cellution | 5 | 5,653 | 43.4 |
| Tortland3 | Cervos BMA — Marrow Cellution | 5 | 4,828 | 55.1 |
| Bianco2 | Cervos BMA — Marrow Cellution | 5 | 5,309 | 68.5 |
| Pooled | Cervos BMA — Marrow Cellution | 37 | 5,010 | 50.5 |
Higher CFU-f counts per mL of bone marrow aspirate concentrate have been directly associated with superior clinical outcomes, and research shows that certain progenitor cell thresholds must be met for meaningful tissue regeneration.6–8
A harvest time of just 2 minutes, compared with the 20 minutes required when using traditional BMAC systems.
High upfront and ongoing costs: centrifuge systems require significant capital investment, routine maintenance and dedicated space, increasing the total cost of the procedure.
Transferring aspirate outside the sterile field for processing introduces additional handling steps, workflow complexity, and contamination and re-entry challenges.
The advantages of Cervos (Marrow Cellution) versus spin systems are it is more efficient for the physician and staff, safer from an infection point of view, and it has equal if not superior regenerative properties from a biological standpoint.
| Item # | Catalog Code | Product Name |
|---|---|---|
| 74376-01M | CER-ORTHO-M | Cervos BMA Ortho — Manual |
| 74381-01M | CER-EXT-M | Cervos BMA Extremity — Manual |
Centrifuge-free bone marrow aspiration uses a precision-engineered cannula with a closed distal tip and lateral side ports to prevent peripheral blood dilution at the source. The result is a clinically meaningful cell concentration without a centrifuge — eliminating capital equipment, sterile-field transfer and the 15–20 minutes of off-field processing time of traditional BMAC workflows. Aspiration to Application® takes less than two minutes.
Across four pooled independent studies (n=37), aspirate obtained using the Marrow Cellution™ device produced a mean CFU-f count of 5,010/mL and a total nucleated cell density of 50.5 million/mL — within the range of cancellous bone autograft (4,564 CFU-f/mL; 55.7M TNC/mL). Harvesting takes about two minutes compared with ~20 minutes for BMAC centrifugation, eliminates the need for capital equipment and keeps the entire procedure within a single sterile field.
A typical bone marrow aspirate harvest using the Marrow Cellution™ device takes about two minutes from access to delivery. The device aspirates directly from cancellous bone through precision side ports, without requiring a centrifuge step. Traditional BMAC workflows typically require 15–20 minutes of off-field processing.
Bone marrow aspirate has been investigated across various areas of orthopaedic and regenerative medicine. The Cervos Marrow Cellution™ device has been used in peer-reviewed studies of applications such as knee osteoarthritis, hip osteoarthritis and labral tears, shoulder osteoarthritis, subchondral bone marrow lesions, spinal fusion augmentation and critical limb ischaemia. Clinical use decisions are made by the treating physician based on the patient, the procedure and the published evidence for the relevant application.
